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ACST-1: Difference between revisions
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(→Design) Tag: visualeditor |
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Halliday A, Harrison M, Hayter E, Kong X, Mansfield A, Marro J, et al. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. ''Lancet''. 2010 Sep 25;376(9746):1074–84. | |||
==Clinical Question== | ==Clinical Question== | ||
<!-- This should be a PICO (Population, Intervention, Comparison, Outcome) style question. As an example, the ACCORD trial's clinical question is shown below, but you should replace it with the clinical question addressed by the trial you're summarizing. --> | <!-- This should be a PICO (Population, Intervention, Comparison, Outcome) style question. As an example, the ACCORD trial's clinical question is shown below, but you should replace it with the clinical question addressed by the trial you're summarizing. --> | ||
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<!-- This section provides a bulleted-list summary of your trial's design. Use the ACCORD trial as a template. Don't worry about the asterisks; they're just bullets for a bulleted list. --> | <!-- This section provides a bulleted-list summary of your trial's design. Use the ACCORD trial as a template. Don't worry about the asterisks; they're just bullets for a bulleted list. --> | ||
* Multicenter, randomized, controlled trial | * Multicenter, blinded, randomized, controlled trial | ||
* N=3,120 | * N=3,120 | ||
** | ** immediate CEA (n=1,560) | ||
** | ** deferral of any carotid procedure (n=1,560) | ||
* Setting: 126 | * Setting: 126 centers in 30 countries | ||
* Enrollment: | * Enrollment: April 1993 to July 2003 | ||
* | * Median follow-up: 9 years | ||
* Analysis: Intention-to-treat | * Analysis: Intention-to-treat | ||
* Primary outcome: perioperative mortality and morbidity (death or stroke within 30 days) and non-perioperative stroke | * Primary outcome: perioperative mortality and morbidity (death or stroke within 30 days) and non-perioperative stroke | ||
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<!-- Ditto for exclusion criteria! --> | <!-- Ditto for exclusion criteria! --> | ||
* | * | ||
===Baseline Characteristics=== | ===Baseline Characteristics=== | ||
<!-- Now summarize what the patients looked like at randomization. An example is shown below, but replace it with the baseline characteristics from the study you're summarizing. --> | <!-- Now summarize what the patients looked like at randomization. An example is shown below, but replace it with the baseline characteristics from the study you're summarizing. --> | ||
* | * | ||
==Interventions== | ==Interventions== | ||
<!-- What were the study's interventions? A bulleted list is a nice way to describe these, hence the asterisks in the ACCORD example below. You should replace that with the relevant interventions from the study you're summarizing. --> | <!-- What were the study's interventions? A bulleted list is a nice way to describe these, hence the asterisks in the ACCORD example below. You should replace that with the relevant interventions from the study you're summarizing. --> | ||
* | * | ||
==Outcomes== | ==Outcomes== | ||