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==Clinical Question==
==Clinical Question==
Can total neoadjuvant therapy (TNT) and a selective watch-and-wait (WW) approach achieve comparable disease-free survival (DFS) to standard therapy, and does the sequence of TNT affect outcomes?
DOES total neoadjuvant therapy (TNT) and a selective watch-and-wait (WW) approach achieve comparable disease-free survival (DFS) to standard therapy, and does the sequence of TNT affect outcomes?


==Bottom Line==
==Bottom Line==
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