ACST-1: Difference between revisions

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Halliday A, Harrison M, Hayter E, Kong X, Mansfield A, Marro J, ''et al.'' 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. ''Lancet''. 2010 Sep 25;376(9746):1074–84.
Halliday A, Harrison M, Hayter E, Kong X, Mansfield A, Marro J, ''et al.'' 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomized trial. ''Lancet''. 2010 Sep 25;376(9746):1074–84.
==Clinical Question==
==Clinical Question==
<!-- This should be a PICO (Population, Intervention, Comparison, Outcome) style question. As an example, the ACCORD trial's clinical question is shown below, but you should replace it with the clinical question addressed by the trial you're summarizing. -->
In patients with asymptomatic significant carotid artery stenosis (≥60%), does immediate carotid endarterectomy (CEA) reduce the stroke risk as compared to deferral of CEA?<!-- This should be a PICO (Population, Intervention, Comparison, Outcome) style question. As an example, the ACCORD trial's clinical question is shown below, but you should replace it with the clinical question addressed by the trial you're summarizing. -->


==Bottom Line==
==Bottom Line==
<!-- What is the one thing you would want to take away from this article? Again, the ACCORD's bottom line is shown below, but you should replace it with yours. -->
<!-- What is the one thing you would want to take away from this article? Again, the ACCORD's bottom line is shown below, but you should replace it with yours. -->


==Major Points==  
==Major Points==
<!-- Now write a succinct paragraph or two describing the major points in the article. Again, ACCORD's major points: -->
The stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1) randomized 3,120 patients to receive immediate or deferred CEA.<!-- Now write a succinct paragraph or two describing the major points in the article. Again, ACCORD's major points: -->


==Guidelines==
==Guidelines==
1,174

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