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ADRENAL (view source)

Revision as of 01:33, 30 January 2018

281 bytes added ,  30 January 2018
→‎Outcomes
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==Outcomes==
==Outcomes==
<!-- Because we're comparing experimental and control groups, we usually start the outcomes section with a sentence like this one from ACCORD, just to be clear. The two single-quotes on each side make italics. -->
''Comparisons are hydrocortisone vs. placebo''
 
''Comparisons are intensive therapy vs. standard therapy.''


<!--The usual formatting leaves out the number of events:
<!--The usual formatting leaves out the number of events:
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===Primary Outcomes===
===Primary Outcomes===
<!-- What were the primary outcomes of the study? Be careful with how stats are written. The name of the outcome starts with a semicolon (;) and the actual statistics for that outcome start with a colon (:), for example: -->
; Death from Any Cause at 90 Days
: 27.9% vs. 28.8% [OR 0.95, 95% CI 0.82 – 1.10; P = 0.50]


;  
===Secondary Outcomes===
:  
; Median time to Shock Reversal, days
: 3 (2-5) vs. 4 (2-9) [HR 1.32, 95% CI 1.23 – 1.41; P < 0.001]
 
; Median time to discharge from the ICU, days(IRQ)
: 10 (5 - 30) vs. 12 (6 - 42) [HR 1.14 (1.06 to 1.23); P < 0.001]
 
; Median time to cessation of initial mechanical ventilation, days (IQR)
: 6 (3 - 18) vs. 7 (3 - 24) [HR 1.13 (1.05 to 1.22); P < 0.001]
 
; Blood Transfusions
: 37% vs. 41% [OR 0.82 (0.72 to 0.94); P = 0.004]
 
; 28 day mortality
: NS


===Secondary Outcomes===
; Recurrence of Shock
<!-- Ditto for secondary outcomes -->
: NS


;  
;  
:
Number of days alive and out of the ICU
Number of days alive and out of the hospital
Recurrence of mechanical ventilation
Rate of renal replacement therapy
Incidence of new-onset bacteremia or fungemia
 


===Subgroup Analysis===
===Subgroup Analysis===
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