ADRENAL: Difference between revisions

ADRENAL (view source)

88 bytes removed , 30 January 2018

m

1,567

edits

@@ Line 104: / Line 104: @@
 ==Outcomes==
 ''Comparisons are hydrocortisone vs. placebo''
-<!--The usual formatting leaves out the number of events:
-group1% vs. group2% (risk ratio, hazard ratio, or risk difference; 95% CI for comparison; P-value; NNT/NNH if needed) -->
 ===Primary Outcomes===
@@ Line 125: / Line 122: @@
 : 37% vs. 41% [OR 0.82 (0.72 to 0.94); P = 0.004]
-; 28 day mortality
+Remainder did not reach statistical significance:
-: NS
+* 28 day mortality
+* Recurrence of Shock
-; Recurrence of Shock
+* Number of days alive and out of the ICU
-: NS
+* Number of days alive and out of the hospital
+* Number of days alive and free from mechanical ventilation
-;
+* Recurrence of mechanical ventilation
-Number of days alive and out of the ICU
+* Use of renal replacement therapy
-Number of days alive and out of the hospital
+* New-onset bacteremia or fungemia
-Recurrence of mechanical ventilation
-Rate of renal replacement therapy
-Incidence of new-onset bacteremia or fungemia
 ===Subgroup Analysis===
-<!-- Was there a subgroup analysis? If so, include a summary of it here. -->
+; Subgroup of Death at 90 days
+: No groups reached statistical significance
+:: Sex
+:: Admission Type
+:: Catecholamine dose (> 15 mcg/min)
+:: APACHE II score (≥ 25)
+:: Time from shock onset to randomization
 ===Adverse Events===
-<!-- Were there significant adverse events recorded other than those listed in the secondary outcomes? If so, list them here -->
 ==Criticisms==