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===Baseline Characteristics===
===Baseline Characteristics===
''Hydrocortisone group displayed''
''Hydrocortisone group displayed''
* Age,y: 62.3 ± 14.9
* Demographics: Age 62 years, male sex 60%
* Male: 60%
* Anthropomorphics: Weight 86 kg
* Weight, kg: 85.8 ± 26.6
* Critical care details: Medical admission 69%, surgical admission 31%, APACHE II score median 24
* Medical Admission: 68%
* Therapy at baseline: Mechanical ventilation 99.8%, antimicrobial therapy 98%, RRT 12%
* Surgical admission: 31%
** Inotropes/vasopressors 99.5%
* APACHE II score, median: 24 (IRQ: 19-29)
* Therapy at baseline:
** Mechanical ventilation: 99.8%
** Inotropes / vasopressors: 99.5%
*** Norepinepherine: 98.4%
*** Norepinepherine: 98.4%
*** Vasopressin: 15.1%
*** Vasopressin: 15.1%
*** Epinepherine: 7.2%
*** Epinepherine: 7.2%
*** Other: 8.5%
*** Other: 8.5%
** Antimicrobial therapy: 98.3%
* Physiological parameters: MAP 72 mm Hg, CVP 12 mm Hg, HR 96 BPM
** Renal-replacement therapy: 12.3%
* Labs: Highest lactate 34 mg/dL, highest bilirubin 1.7 mg/dL, highest creatinine 2.2 mg/dL, lowest PaO<sub>2</sub>:F<sub>I</sub>O<sub>2</sub> 165, highest WBC count 17 cells/10<sub>-9</sub>/L
* MAP: 72.5 ± 8.2
* Primary site of infection: Pulmonary 34%, abdominal 26%, blood 17%, skin/soft tissue 7%, urinary 8%, other 8%
* Primary site of infection:
* Time from ICU admission to randomization: 26 hours
** Pulmonary: 39%
* Time from shock onset to randomization: 21 hours
** Abdominal: 26%
** Blood: 17%
** Skin/Soft tissue: 7%
** Urinary: 8%
** Other: 8%
* Time from ICU admission to randomization, h: 26.1 ± 70.7
* Time from shock onset to randomization, h: 20.9 ± 91.9


==Interventions==
==Interventions==
Bureaucrats, editor, reviewer, Administrators
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