Bureaucrats, editor, reviewer, Administrators
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===Baseline Characteristics=== | ===Baseline Characteristics=== | ||
''Hydrocortisone group displayed'' | ''Hydrocortisone group displayed'' | ||
* Age, | * Demographics: Age 62 years, male sex 60% | ||
* Anthropomorphics: Weight 86 kg | |||
* Weight | * Critical care details: Medical admission 69%, surgical admission 31%, APACHE II score median 24 | ||
* Medical | * Therapy at baseline: Mechanical ventilation 99.8%, antimicrobial therapy 98%, RRT 12% | ||
** Inotropes/vasopressors 99.5% | |||
* Therapy at baseline: | |||
** Inotropes / vasopressors | |||
*** Norepinepherine: 98.4% | *** Norepinepherine: 98.4% | ||
*** Vasopressin: 15.1% | *** Vasopressin: 15.1% | ||
*** Epinepherine: 7.2% | *** Epinepherine: 7.2% | ||
*** Other: 8.5% | *** Other: 8.5% | ||
* | * Physiological parameters: MAP 72 mm Hg, CVP 12 mm Hg, HR 96 BPM | ||
* Labs: Highest lactate 34 mg/dL, highest bilirubin 1.7 mg/dL, highest creatinine 2.2 mg/dL, lowest PaO<sub>2</sub>:F<sub>I</sub>O<sub>2</sub> 165, highest WBC count 17 cells/10<sub>-9</sub>/L | |||
* | * Primary site of infection: Pulmonary 34%, abdominal 26%, blood 17%, skin/soft tissue 7%, urinary 8%, other 8% | ||
* Primary site of infection: | * Time from ICU admission to randomization: 26 hours | ||
* Time from shock onset to randomization: 21 hours | |||
* Time from ICU admission to randomization | |||
* Time from shock onset to randomization | |||
==Interventions== | ==Interventions== |