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→Inclusion Criteria
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* strong clinical suspicion of infection | * strong clinical suspicion of infection | ||
* ≥2 SIRS criteria <ref>{{#pmid:1303622}}</ref> | * ≥2 SIRS criteria <ref>{{#pmid:1303622}}</ref> | ||
** ''Note | ** ''Note: Alignment between participants and newer SEPSIS-3 definitions are presented in the supplementary appendix in Table S2c on page 11.''<ref name="supapp">[http://www.nejm.org/doi/suppl/10.1056/NEJMoa1705835/suppl_file/nejmoa1705835_appendix.pdf Supplementary appendix]</ref> | ||
* Continuous vasopressors/inotropes for SBP >90mmHg or MAP >60mmHg for ≥4 hours | * Continuous vasopressors/inotropes for SBP >90mmHg or MAP >60mmHg for ≥4 hours | ||