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→Secondary Outcomes
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===Secondary Outcomes=== | ===Secondary Outcomes=== | ||
; | ; 28-day mortality | ||
: 3 | : 22.3% vs. 24.3% (OR 0.89; 95% CI 0.76-1.03; P=0.13) | ||
; Median time to | ; Median time to shock reversal, days (IQR) | ||
: | : 3 (2-5) vs. 4 (2-9) (HR 1.32; 95% CI 1.23–1.41; P<0.001) | ||
; | ; Recurrence of shock | ||
: | : 19.7% vs. 18.4% (OR 1.07; 95% CI 0.94-1.22; P=0.32) | ||
; | ; Median time to discharge, days (IQR) | ||
: | : '''From ICU''': 10 (5-30) vs. 12 (6-42) (HR 1.14; 95% CI 1.06-1.23; P<0.001) | ||
: '''From the hospital''': 39 (19-NA) vs 43 (19-NA) (HR 1.06; 95% CI 0.98-1.15; P=0.13) | |||
; | ; Duration of initial mechanical ventilation, days (IQR) | ||
: | : 6 (3-18) vs. 7 (3-24) (HR 1.13; 95% CI 1.05-1.22; P<0.001) | ||
; Days alive and free from mechanical ventilation | |||
: | : 61.2 vs. 59.1 days (Mean absolute difference 2.18, 95% CI -0.11 to 4.46; P=0.06) | ||
: | |||
: | ; Frequency of RRT | ||
: 30.6% vs. 32.7% (OR 0.94; 95% CI 0.86-1.03; P=0.18) | |||
; Days alive and free from RRT | |||
: 42.6 vs. 40.4 days (Mean absolute difference 2.37, 95% CI -2.00 to 6.75; P=0.29) | |||
; Incident new-onset bacteremia or fungemia | |||
: 14.1% vs. 14.1% (OR 1.00; 95% CI 0.86-1.16; P=0.96) | |||
; Blood transfusion | |||
: 37.0% vs. 41.7% (OR 0.82; 95% CI 0.72-0.94; P=0.004) | |||
===Subgroup Analysis=== | ===Subgroup Analysis=== | ||