WikiJournalClub:Top Trials Series/Cardiology

The Top 10 Trials in Congestive Heart Failure

• 1991 SOLVD Enalapril in CHF with EF <35% [1]
• 1991 V-HeFTII Hydralazine & nitrates vs. Ace-inhibitors in CHF [2]
• 1986 V-HeFT ISDN/hydralazine in CHF [3]
• 1996 US Carvedilol HF Carvedilol in CHF [4]
• 1999 MERIT-HF Metoprolol CR/XL in CHF [5]
• 2003 COMET Carvedilol vs. metoprolol tartrate in CHF [6]
• 1999 RALES Spironolactone in NYHA III/IV CHF & EF <= 35% [7]
• 2001 Val-HeFT Valsartan in CHF [8]
• 1997 DIG Digoxin in CHF with LVEF ≤45%[9]
• 2002 MADIT-II ICD in post-MI CHF with LVEF ≤30 [10]