A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis

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. "Journal of Trauma and Acute Care Surgery". '. . :.
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Clinical Question

Among patients with

Bottom Line

Major Points

Clostridium Difficile-Associated Disease (CDAD) is a ful Pittsburg protocol for DLI with irrigation and vancomycin [1]

Guidelines

Design

  • Design: Retrospective, multicenter study
  • Setting: 10
  • Enrollment:
  • Mean follow-up:
  • Analysis:
  • Primary outcome:

Population

Inclusion Criteria

Exclusion Criteria

  • Tracheostomy

Baseline Characteristics

Interventions

Outcomes

Comparisons are intensive therapy vs. standard therapy.

Primary Outcomes

Secondary Outcomes

Subgroup Analysis

Adverse Events

Criticisms

Funding

Further Reading

  1. Neal MD et al. Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease. Ann Surg 2011. 254:423-7; discussion 427-9.