A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis

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Clinical Question

Among patients with

Bottom Line

Major Points

Clostridium Difficile-Associated Disease (CDAD) is a ful Pittsburg protocol for DLI with irrigation and vancomycin [1]

Guidelines

Design

  • Design: Retrospective, multicenter study
  • Setting: 10
  • Enrollment:
  • Mean follow-up:
  • Analysis:
  • Primary outcome:

Population

Inclusion Criteria

Exclusion Criteria

  • Tracheostomy

Baseline Characteristics

Interventions

Outcomes

Comparisons are intensive therapy vs. standard therapy.

Primary Outcomes

Secondary Outcomes

Subgroup Analysis

Adverse Events

Criticisms

Funding

Further Reading

  1. ↑ Neal MD et al. Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease. Ann Surg 2011. 254:423-7; discussion 427-9.
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