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         },
         },
         {
         {
             "timestamp" : "2023-03-04T09:33:33Z",
             "timestamp" : "2025-05-22T17:33:23Z",
             "briefDesignDescription" : "Aspirin for ASCVD 1° prevention if age >70",
             "briefDesignDescription" : "Aspirin for ASCVD 1° prevention if age >70",
             "fulltexturl" : "https://www.nejm.org/doi/full/10.1056/NEJMoa1800722",
             "fulltexturl" : "https://www.nejm.org/doi/full/10.1056/NEJMoa1800722",
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             "published" : "2018-09-16",
             "published" : "2018-09-16",
             "pageName" : "ASPREE",
             "pageName" : "ASPREE",
             "diseases" : "Atherosclerotic Coronary Artery Disease",
             "diseases" : "Coronary Artery Disease",
             "abbreviation" : "ASPREE",
             "abbreviation" : "ASPREE",
             "title" : "Effect of aspirin on disability-free survival in the healthy elderly",
             "title" : "Effect of aspirin on disability-free survival in the healthy elderly",
Line 1,277: Line 1,277:
         },
         },
         {
         {
             "timestamp" : "2023-02-07T21:36:04Z",
             "timestamp" : "2025-05-22T17:32:42Z",
             "briefDesignDescription" : "DOAC, VKA, antiplatelets after PCI with stent and AF",
             "briefDesignDescription" : "DOAC, VKA, antiplatelets after PCI with stent and AF",
             "fulltexturl" : "https://www.nejm.org/doi/full/10.1056/NEJMoa1817083",
             "fulltexturl" : "https://www.nejm.org/doi/full/10.1056/NEJMoa1817083",
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             "published" : "2019-04-18",
             "published" : "2019-04-18",
             "pageName" : "AUGUSTUS",
             "pageName" : "AUGUSTUS",
             "diseases" : "Coronary artery disease;Atrial Fibrillation",
             "diseases" : "Coronary Artery Disease;Atrial Fibrillation",
             "abbreviation" : "AUGUSTUS",
             "abbreviation" : "AUGUSTUS",
             "title" : "Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation",
             "title" : "Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation",
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         },
         },
         {
         {
             "timestamp" : "2018-11-30T20:42:52Z",
             "timestamp" : "2025-05-22T17:32:54Z",
             "briefDesignDescription" : "Low-dose MTX for secondary prevention of CAD",
             "briefDesignDescription" : "Low-dose MTX for secondary prevention of CAD",
             "fulltexturl" : "https://www.nejm.org/doi/full/10.1056/NEJMoa1809798",
             "fulltexturl" : "https://www.nejm.org/doi/full/10.1056/NEJMoa1809798",
Line 2,221: Line 2,221:
             "published" : "2018-11-10",
             "published" : "2018-11-10",
             "pageName" : "CIRT",
             "pageName" : "CIRT",
             "diseases" : "Coronary artery disease",
             "diseases" : "Coronary Artery Disease",
             "abbreviation" : "CIRT",
             "abbreviation" : "CIRT",
             "title" : "Low-dose methotrexate for the prevention of atherosclerotic events",
             "title" : "Low-dose methotrexate for the prevention of atherosclerotic events",
Line 3,992: Line 3,992:
             "title" : "Effect of finerenone on chronic kidney disease outcomes in type 2 diabetes",
             "title" : "Effect of finerenone on chronic kidney disease outcomes in type 2 diabetes",
             "pmid" : "33264825"
             "pmid" : "33264825"
        },
        {
            "timestamp" : "2025-05-22T17:37:48Z",
            "briefDesignDescription" : "Lifestyle interventions to prevent diabetes",
            "fulltexturl" : "http://www.nejm.org/doi/full/10.1056/NEJM200105033441801#t",
            "pageid" : 2776,
            "pdfurl" : "http://www.nejm.org/doi/pdf/10.1056/NEJM200105033441801",
            "trainingLevel" : "Resident",
            "citation" : "Tuomilehto J, <i>et al</i>. \"Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle among Subjects with Impaired Glucose Tolerance\". <i>The New England Journal of Medicine</i>. 2001. 344(18):1343-1350.",
            "subspecialties" : "Endocrinology",
            "expansion" : "",
            "statusUsableDate" : "2025-06-01",
            "briefResultsDescription" : "Intensive lifestyle interventions prevent diabetes",
            "published" : "2001-15-03",
            "pageName" : "Finnish Diabetes Prevention Study",
            "diseases" : "Diabetes Mellitus",
            "abbreviation" : "Finnish Diabetes Prevention Study",
            "title" : "Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle among Subjects with Impaired Glucose Tolerance",
            "pmid" : "11333990"
         },
         },
         {
         {
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         },
         },
         {
         {
             "timestamp" : "2023-08-03T17:47:16Z",
             "timestamp" : "2025-05-22T17:32:19Z",
             "briefDesignDescription" : "PUFA in patients with heart failure",
             "briefDesignDescription" : "PUFA in patients with heart failure",
             "fulltexturl" : "http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61239-8/fulltext",
             "fulltexturl" : "http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61239-8/fulltext",
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             "published" : "2008-10-04",
             "published" : "2008-10-04",
             "pageName" : "GISSI-HF",
             "pageName" : "GISSI-HF",
             "diseases" : "Heart failure",
             "diseases" : "Heart Failure",
             "abbreviation" : "GISSI-HF",
             "abbreviation" : "GISSI-HF",
             "title" : "Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure",
             "title" : "Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure",
Line 4,239: Line 4,258:
             "title" : "Mild Therapeutic Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest",
             "title" : "Mild Therapeutic Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest",
             "pmid" : "11856793"
             "pmid" : "11856793"
        },
        {
            "timestamp" : "2025-05-22T17:34:50Z",
            "briefDesignDescription" : "High- vs. low-dose losartan in heart failure",
            "fulltexturl" : "http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)61913-9/fulltext",
            "pageid" : 2825,
            "pdfurl" : "http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(09)61913-9.pdf",
            "trainingLevel" : "resident",
            "citation" : "Konstam MA, <i>et al</i>. \"Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure\". <i>The Lancet</i>. 2009. 374(9704):1840-1848.",
            "subspecialties" : "Cardiology",
            "expansion" : "Heart failure Endpoint evaluation of Angiotensin II Antagonist Losartan",
            "statusUsableDate" : "2025-05-12",
            "briefResultsDescription" : "High-dose losartan improves HF outcomes",
            "published" : "2009-11-28",
            "pageName" : "HEAAL",
            "diseases" : "Heart Failure",
            "abbreviation" : "HEAAL",
            "title" : "Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure",
            "pmid" : "19922995"
         },
         },
         {
         {
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             "title" : "Randomized study of basal-bolus insulin therapy in the inpatient management of patients with type 2 diabetes (RABBIT 2 trial)",
             "title" : "Randomized study of basal-bolus insulin therapy in the inpatient management of patients with type 2 diabetes (RABBIT 2 trial)",
             "pmid" : "17513708"
             "pmid" : "17513708"
        },
        {
            "timestamp" : "2025-05-22T17:30:01Z",
            "briefDesignDescription" : "Delayed vs. early cardioversion in AF",
            "fulltexturl" : "https://www.nejm.org/doi/10.1056/NEJMoa1900353",
            "pageid" : 4062,
            "pdfurl" : "https://www.nejm.org/doi/pdf/10.1056/NEJMoa1900353",
            "trainingLevel" : "Resident",
            "citation" : "Pluymaekers NAHA, <i>et al</i>. \"Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation\". <i>The New England Journal of Medicine</i>. 2019. 380(16):1499-1508.",
            "subspecialties" : "Emergency Medicine;Cardiology",
            "expansion" : "Rate Control versus Electrical Cardioversion Trial 7–Acute Cardioversion versus Wait and See",
            "statusUsableDate" : "2025-05-25",
            "briefResultsDescription" : "Delayed is noninferior to early cardioversion in obtaining sinus rhythm",
            "published" : "2019-04-18",
            "pageName" : "RACE 7 ACWAS",
            "diseases" : "Atrial Fibrillation",
            "abbreviation" : "RACE 7 ACWAS",
            "title" : "Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation",
            "pmid" : "30883054"
         },
         },
         {
         {
Line 7,374: Line 7,431:
             "title" : "Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus",
             "title" : "Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus",
             "pmid" : "22335736"
             "pmid" : "22335736"
        },
        {
            "timestamp" : "2025-05-22T17:14:03Z",
            "briefDesignDescription" : "Chemo-RT vs. chemo in rectal cancer",
            "fulltexturl" : "https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(20)30555-6/fulltext",
            "pageid" : 5600,
            "pdfurl" : "https://www.thelancet.com/action/showPdf?pii",
            "trainingLevel" : "Fellow",
            "citation" : "Bahadoer RR, <i>et al</i>. \"Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial\". <i>The Lancet Oncology</i>. 2021. 22(1):29-42.",
            "subspecialties" : "Oncology",
            "expansion" : "Rectal Cancer and Preoperative Induction Therapy Followed by Dedicated Operation Trial",
            "statusUsableDate" : "2025-05-22",
            "briefResultsDescription" : "Fewer treatment failures with chemo-RT",
            "published" : "2021-01-01",
            "pageName" : "RAPIDO",
            "diseases" : "Colorectal Cancer",
            "abbreviation" : "RAPIDO",
            "title" : "Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial",
            "pmid" : "33301740"
         },
         },
         {
         {
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